Schematic illustration of IMAMs penetrating mucus and biofilm for the immunoantibacterial therapy of COPD.(A) A scheme illustrating the development of IMAMs (MEKCA/CAZ NPs). (B) A scheme illustrating IMAMs penetrating mucus and biofilm, adopted by the cost/conformation transformation within the acidic surroundings. MEKCA NPs synergize with CAZ to get rid of bacterial an infection, scavenge eDNA